Freespira, Inc.

Recognizing the need for alternative and more condition specific treatments, many health plans are improving access and personalization to mental health solutions that impact overall spend while providing relief for members in less time. Freespira is a first-in- class FDA-cleared, medication-free digital therapeutic indicated for treatment of Panic Disorder and Post Traumatic Stress Disorder (PTSD). Freespira addresses a common underlying physiological factor of panic attacks and PTSD symptoms, a hypersensitivity to carbon dioxide (CO2), which can lead to chronic respiratory dysregulation and bodily hypervigilance, a leading factor of panic attacks and PTSD flashbacks. Freespira normalizes CO2 and respiratory rates in a single 28-day treatment—delivering clinical improvement at lower cost. Guided, twice-daily treatments use a sensor sampling the patients exhaled air (to measure exhaled CO2 levels and respiration rates). These physiological indicators are displayed in real-time on a tablet as visual feedback along with rising and falling audio tones to teach patients how to normalize respiration rate and expired CO2 levels. Concurrent coaching offers education and promotes patient engagement.